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Polymorphous sweat gland carcinoma: a report of two cases
Author(s) -
Walker Addie,
Mesinkovska Natasha A.,
Emanuel Patrick O.,
Vidimos Allison,
Billings Steven D.
Publication year - 2016
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.12695
Subject(s) - sweat gland , pathology , differential diagnosis , adenocarcinoma , eccrine sweat gland , neoplasm , medicine , carcinoma , sweat , cancer
Polymorphous sweat gland carcinoma ( PSGC ) is a rare adnexal neoplasm with characteristic variegated histopathologic findings and low‐grade clinical behavior. First described in 1994, only 11 cases have been reported in the literature. It is named for the multiplicity of architectural patterns that may be present: solid, tubular, trabecular, pseudopapillary and cylindromatous. Owing to the multiple architectural patterns, the differential diagnosis is broad, including metastatic adenocarcinoma and other adnexal neoplasms with ductular differentiation. We present two new cases of PSGC and review the literature on this rare tumor.