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Cutaneous histiocytoid Sweet syndrome and its relationship to hematological diseases
Author(s) -
Bush James W.,
Wick Mark R.
Publication year - 2016
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.12659
Subject(s) - dyscrasia , myeloproliferative disorders , pathology , medicine , myeloid , myelodysplastic syndromes , haematopoiesis , leukemia , sweet syndrome , dermatology , immunology , bone marrow , stem cell , biology , plasma cell , genetics
Sweet syndrome ( SS ) was described over 50 years ago as a distinctive form of neutrophilic dermatosis. It may be idiopathic, drug‐induced or paraneoplastic, and in the last of those subtypes, myeloproliferative diseases are prominently represented. A peculiar variant of SS is termed ‘histiocytoid’ SS ( HSS ), and early accounts of that condition asserted that it showed no linkage to hematological disorders. We herein report two additional cases of HSS – both of which were associated with myeloid dyscrasias – together with a review of the pertinent literature. Along with our observations, the latter process appears to contradict the contention that HSS has no relationship to hematopoietic diseases; between 35 and 55% of reported cases have indeed shown such an association, usually with myelogenous leukemia or myelodysplastic syndromes.