Premium
Follicular necrotic keratinocytes – a helpful clue to the diagnosis of measles
Author(s) -
Tirado Mariantonieta,
Adamzik Karoline,
BöerAuer Almut
Publication year - 2015
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.12529
Subject(s) - pathology , multinucleate , measles , biology , cytoplasmic inclusion , cytoplasm , keratin , follicular phase , eosinophilic , measles virus , medicine , microbiology and biotechnology , endocrinology , vaccination
A skin specimen taken from the exanthem of a 22‐year‐old man with measles infection was examined by light microscopy. The most characteristic changes were foci of multiple necrotic keratinocytes, partially confluent and partially isolated, strictly within follicles and sebaceous glands. Serial sections revealed occasional necrotic and none‐necrotic syncytial‐type multinucleated epithelial cells in some infundibula. Neither nuclear nor cytoplasmic viral inclusions were present.