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Glomus‐like bodies within a neurofibroma: a novel neoplasm arising in neurofibromatosis type 1 or a coincidence?
Author(s) -
Thareja Sumeet,
Honigbaum Alexis,
Jukic Drazen
Publication year - 2015
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.12439
Subject(s) - neurofibroma , neurofibromatosis , glomus tumor , pathology , neoplasm , phenotype , biology , medicine , genetics , gene
Neurofibromatosis type 1 is a relatively common genetic disorder with variable phenotypes. Tumors with features of both glomus tumors and neurofibromas are exceedingly rare in literature. Herein, we report a not yet described neoplasm with features of both a glomangioma/glomus tumor and a neurofibroma arising in a patient with segmental neurofibromatosis. Our case report supports the theory of a common lineage/ancestor cell between neurofibromas and glomus tumors and adds it to the spectrum of neoplasms that may arise in the setting of Von Recklinghausen's disease.