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CD8 ‐positive peripheral T‐cell lymphoma with aberrant expression of CD20 and concurrent in situ follicular lymphoma
Author(s) -
Sagasta Amaia,
MolinaUrra Ricardo,
Martinez Daniel,
GonzalezFarre Blanca,
Marti Esther,
Herranz Maria Jose,
Estrach Teresa,
Campo Elias,
Colomo Lluis
Publication year - 2015
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.12409
Subject(s) - lymphoma , pathology , medicine , peripheral t cell lymphoma , follicular lymphoma , cd20 , biopsy , immunohistochemistry , lymph node , cd8 , lymph node biopsy , skin biopsy , t cell , antigen , immunology , immune system
A case of a 78‐year‐old woman with a CD8 ‐positive peripheral T‐cell lymphoma with aberrant expression of CD20 associated with follicular lymphoma in situ ( FLIS ) is reported. The neoplasm presented initially as cutaneous macules, papules, plaques and nodules. A skin biopsy was performed and the diagnosis of peripheral T‐cell lymphoma ( PTCl ) with aberrant expression of CD20 was made. The staging procedures included an excisional inguinal lymph node biopsy that showed findings similar to those of the previous diagnosis. In addition, FLIS was identified. The clinicopathologic features of PTCLs with aberrant CD20 expression involving the skin as well as this uncommon association are reviewed.