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Spindle‐cell variant of primary cutaneous follicle center lymphoma spreading to the hepatobiliary tree, mimicking Klatskin tumor
Author(s) -
Rozati Sima,
Kerl Katrin,
Kempf Werner,
Tinguely Marianne,
Zimmermann Dieter R.,
Dummer Reinhard,
Cozzio Antonio
Publication year - 2013
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/cup.12017
Subject(s) - pathology , lymphoma , medicine , biology
Primary cutaneous follicle center lymphoma ( pcFCL ) is an indolent type of primary cutaneous B‐cell lymphoma ( pcBCL ) rarely disseminating to other organs. PcBCL with spindle‐cell morphology has been described as a rare variant of pcFCL but the prognosis data of this variant is sparse. We report a rare case of spindle‐cell pcFCL with CD20 + , CD79a + , CD3 + , Bcl‐6 + , Mum‐1 − and CD10 − tumor cells that infiltrated the hepatic hilum, mimicking a Klatskin tumor. On the basis of the sparse published data on spindle‐cell morphology of pcBCL , this growth pattern should elicit awareness of an increased risk of systemic involvement in the otherwise indolent pcFCL .