Open AccessTreatments and Preventative Measures for Trauma‐Induced Heterotopic Ossification: A Review
Author(s) -
Juarez Jessica K.,
Wenke Joseph C.,
Rivera Jessica C.
Publication year - 2018
Publication title -
clinical and translational science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 44
eISSN - 1752-8062
pISSN - 1752-8054
DOI - 10.1111/cts.12552
Subject(s) - heterotopic ossification , medicine , surgery , soft tissue , ossification , acetabular fracture , synostosis , acetabulum
Heterotopic ossification (HO) is derived from the Greek terms “heteros” (“other”), topos (“place”), and “ossification,” a Latin‐derived term for “to turn to bone.” HO references lamellar bone ossifying in aberrant locations, such as in joints and muscle. It has been cited through medical history, dating to 1,000 C.E. when Al‐Zahrawi described a complication of fracture as a “callus often occurs after the healing of a fracture…and sometimes there is limitation of the natural function of the limb…”.1 Outside of rare genetic forms of HO, any state that causes local soft tissue damage, such as high‐energy trauma injuries and surgical approaches, can cause HO.2 Because of its correlation with trauma, HO is among the postinjury and iatrogenic complications that can cause pain and impact a patient's recovery and rehabilitation efforts.3