Open AccessSufficiency of Single‐Arm Studies to Support Registration of Targeted Agents in Molecularly Selected Patients with Cancer: Lessons from the Clinical Development of Crizotinib
Author(s) -
Selaru P,
Tang Y,
Huang B,
Polli A,
Wilner KD,
Donnelly E,
Cohen DP
Publication year - 2016
Publication title -
clinical and translational science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 44
eISSN - 1752-8062
pISSN - 1752-8054
DOI - 10.1111/cts.12388
Subject(s) - crizotinib , medicine , clinical trial , drug development , tolerability , anaplastic lymphoma kinase , lung cancer , oncology , adverse effect , cancer , drug , pharmacology , malignant pleural effusion