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Living donor liver transplantation in septuagenarians: Better late than never
Author(s) -
Zidan Ahmed,
Sturdevant Mark,
Elsarawy Ahmed,
Hassan Ramy,
Alabbad Saleh,
Alghamdi Saad,
Bzeizi Khalid,
Broering Dieter C.
Publication year - 2021
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/ctr.14301
Subject(s) - medicine , liver transplantation , cohort , life expectancy , transplantation , comorbidity , population , liver disease , blood product , surgery , environmental health
Background The coupling of increased life expectancy and improvements in both quality and access to chronic liver disease care, is culminating in an expanding population of septuagenarians (≥70 years) in need of liver transplantation (LT). The objective of this study is to partially alleviate this knowledge deficit and to add clarity to the current status and role of LDLT in this recipient population. Methods Of 295 adult patients underwent LDLT between January 1, 2011 and December 31, 2016. Twelve (4%) of these patients were septuagenarians and this group was compared to younger cohort ( n = 283). Results Comorbidity profiles between the two groups were similar and no statistically significant differences were noted in warm/cold ischemia times, operative duration, or blood product utilization. ICU and total hospital stays were comparable. Septuagenarian 1‐and 5‐year graft and patient survivals were identical at 91.7%. Their younger counterparts had 1‐and 5‐year patient survivals of 91.1% and 84.0 % accompanied by 1‐and 5‐year graft survivals of 89.8% and 82.7%, respectively. Conclusion Our study highlights a recognition that LDLT can afford highly‐selected elderly patients to access to transplant with equivalent outcomes to those realized by younger recipients.