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Orthotopic liver transplant in the pregnant recipient: A systematic review of preoperative management and maternal and fetal outcomes
Author(s) -
Romano Dia.,
Mokuolu Debbie C.,
Katz Daniel J.,
DeMaria Jr Samuel
Publication year - 2021
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/ctr.14269
Subject(s) - medicine , liver transplantation , perioperative , pregnancy , transplantation , etiology , fetus , maternal morbidity , intensive care medicine , gestation , surgery , obstetrics , genetics , biology
Severe liver dysfunction requiring transplantation is a major event at any stage of life, but for those requiring liver transplantation while pregnant, two lives hang in the balance. Available evidence on this relatively rare event consists solely of case reports and have yet to be reviewed or synthesized. We performed a systematic literature review and analyzed reports of 22 patients who underwent liver transplantation during pregnancy. This review describes the reported etiologies of hepatic failure in pregnant patients requiring transplantation, perioperative anesthetic management techniques, and the maternal and fetal clinical outcomes.