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Doppler‐derived renal resistive index helps predict acute kidney injury in patients undergoing living‐related liver transplantation
Author(s) -
Shankar Vijay,
Raj Anupam,
Singhal Saurabh,
Sahni Reeti,
Goyal Neerav,
Venuthurimilli Arun,
Olson Michael T.,
Chatterji Chitra
Publication year - 2021
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/ctr.14263
Subject(s) - medicine , resistive index , acute kidney injury , prospective cohort study , transplantation , single center , kidney transplantation , kidney , surgery , urology , ultrasonography
Background Acute kidney injury (AKI) is commonly associated with increased postoperative morbidity in liver transplant (LT) recipients. The aim of this study was to identify the role of renal resistive index (RRI) in predicting AKI and to study the factors associated with AKI in LT recipients. Patients and methods We performed a single‐center, prospective study, including adult living donor LT recipients at our center between January 2018 and September 2019 with no preoperative renal dysfunction. RRI was calculated on ultrasound doppler once preoperatively, and once daily in the postoperative period through postoperative day (POD) six. Patients were grouped into AKI and non‐AKI groups for comparison. Results Fifty patients were included in the study (mean age, 44 years; 20% females). AKI developed in 25 patients (50%). Both groups were similar in baseline characteristics. RRI of ≥ 0.69 on POD 2 predicted AKI (sensitivity 88%; specificity 92%). RRI on the day before AKI diagnosis (0.71 vs. 0.65) and on the day of diagnosis (0.72 vs. 0.65) were significantly increased relative to preoperative baseline. Conclusions Doppler‐derived RRI is a rapid, non‐invasive, and bedside procedure capable of predicting the occurrence of postoperative AKI in LT recipients.