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Characteristics of compatible pair participants in kidney paired donation at a single center
Author(s) -
Weng Francis L.,
Grogan Tracy,
Patel Anup M.,
Mulgaonkar Shamkant,
Morgievich Marie M.
Publication year - 2017
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/ctr.12978
Subject(s) - medicine , kidney donation , kidney transplant , kidney , single center , donation , kidney transplantation , blood donor , surgery , body mass index , immunology , economic growth , economics
Compatible pairs of living kidney donors and their intended recipients can enter into kidney paired donation ( KPD ) and facilitate additional living donor kidney transplants ( LDKT s). We examined 11 compatible pairs (the intended recipients and their intended, compatible donors) who participated in KPD , along with the recipients’ 11 matched, exchange donors. The 11 pairs participated in 10 separate exchanges (three were multicenter exchanges) that included 33 total LDKT s (22 additional LDKT s). All the intended donors were blood group O and female, with a mean living kidney donor profile index ( LKDPI ) of 27.6 ( SD 16.8). The matched donors had a mean LKDPI of 9.4 ( SD 31.7). Compatible pairs entered KPD for altruistic reasons (N=2) or due to mismatch of age (N=7) or body/kidney size (N=2) between the recipient and intended donor. In four cases, retrospective calculation of the LKDPI revealed that the matched donor had a higher LKDPI than the intended donor. Of the 22 recipients of LDKT s enabled by the compatible pairs, three were highly sensitized, with PRA >80%. In conclusion, most compatible pairs entered into KPD so that the recipient could receive a LDKT transplant from a donor whose age or body/kidney size were more favorable to post‐transplant outcomes.