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Comparison of live donor pre‐transplant and recipient post‐transplant renal volumes
Author(s) -
Yanishi Masaaki,
Kinoshita Hidefumi,
Yoshida Takashi,
Takayasu Kenta,
Yoshida Kenji,
Mishima Takao,
Sugi Motohiko,
Tsukaguchi Hiroyasu,
Kawa Gen,
Matsuda Tadashi
Publication year - 2016
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/ctr.12727
Subject(s) - medicine , renal transplant , renal function , kidney , urology , kidney transplant , kidney transplantation , transplantation , gastroenterology
Background Live donor pre‐transplant and recipient post‐transplant kidney volumes based on three‐dimensional computed tomography (3 DCT ) have been related to post‐transplant renal function. We examined this association and the effect of sex/size differences between donor and recipient on kidney growth rate. Methods We retrospectively reviewed 30 live donors who underwent pre‐transplant and post‐transplant 3 DCT . We determined donor (Dvol) and recipient renal volumes (Rvol) based on 3 DCT and calculated changes in graft volume after transplantation (Vol‐ratio). We also divided Dvol by recipient body weight (Dvol/ RW gt) and compared the correlations between Vol‐ratio and Dvol/ RW gt and post‐transplant renal function after one yr. We determined the rates of change in kidney volume and renal function according to the sexes of the donor and recipient. Results The mean Dvol and Rvol were 141.7 and 178.4 mL, respectively. The mean Vol‐ratio was 127.3%. Dvol/RWgt showed a significant linear correlation with remaining renal function after one yr ( r = 0.6745, p < 0.0001). The combination of female donor and male recipient resulted in the fastest increase in kidney volume (p < 0.001) and highest level of proteinuria (p < 0.001). Conclusions Pre‐transplant and post‐transplant kidney volumes are correlated with post‐transplant graft function, and graft growth is affected by the relative sexes of the recipient and donor.