Comparing 10‐yr renal outcomes in deceased donor and living donor liver transplants

Few studies have explored whether the type of LT , deceased donor LT ( DDLT ) or living donor LT ( LDLT ), impacts long‐term renal outcomes. We performed a retrospective analysis of 220 LT recipients at our institution to study their renal outcomes at 10 yr. Exclusion criteria were age ≤ 18 yr, graft survival ≤6 months, and multiorgan transplants; 108 DDLT s and 62 LDLT s were eligible. At baseline, DDLT s had a lower eGFR than LDLT s and 10.2% of DDLT s were on dialysis as compared to 0% of LDLT s. At 10 yr, seven DDLT and three LDLT recipients required dialysis or renal transplant (p = 0.75). In recipients with graft survival >6 months, DDLT s had a slower decline in eGFR as compared to LDLT s (p < 0.01). Among LDLT s, the decline in eGFR continued over the entire 10‐yr period, whereas among DDLT s, the decline in eGFR slowed significantly after six months (p = 0.01). This difference between the two groups was not seen among patients in the highest quartile of baseline eGFR . Patient survival and graft survival were similar. In conclusion, the incidence of end‐stage renal disease was similar in both DDLT and LDLT patients, but LDLT recipients seem to have a more sustained decline in eGFR when compared with DDLT recipients.