z-logo
Premium
Outcome of organs procured from donors on extracorporeal membrane oxygenation support: an analysis of kidney and liver allograft data
Author(s) -
Bodzin Adam S.,
Hirose Hitoshi,
West Sharon,
Hasz Richard,
Maley Warren R.,
Cavarocchi Nicholas C.
Publication year - 2014
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/ctr.12384
Subject(s) - medicine , extracorporeal membrane oxygenation , organ donation , retrospective cohort study , kidney , surgery , oxygenation , transplantation , organ procurement , anesthesia
Extracorporeal membrane oxygenation has become rescue therapy for adults with overwhelming cardiac and/or respiratory failure. Not all patients are saved, creating a new cohort of potential organ donors. This study examines the outcomes of liver and kidney allografts procured from donors on extracorporeal membrane oxygenation ( ECMO ). Methods A retrospective review was conducted through the local organ procurement organization. Donors on ECMO prior to notification were classified into donation after brain death ( DBD ) and donation after cardiac death ( DCD ). We compared short‐term outcome data against published standards. Results Between 1995 and 2012, 97 organs were procured from 41 donors supported on ECMO . There were 68 kidneys donated, 51 were transplanted and 17 discarded. Excluding extended criteria donors, 29 DBD and 13 DCD kidneys were transplanted from donors supported on ECMO . Delayed graft function occurred in 34% of DBD kidneys and 38% of DCD kidneys. Kidney allograft survival at one yr was 93%. Twenty‐four livers were procured, nine discarded, and 15 transplanted. Ninety‐three percent of liver transplant recipients were alive with graft function at one yr. Conclusions Donation after brain death kidneys procured from donors on ECMO perform similarly to non‐ ECMO organs with regard to delayed graft function ( DGF ), one‐yr graft survival and function. Livers from ECMO donors have a higher discard rate than non‐ ECMO donors, but function similarly at six months and one yr.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here