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Does comfort therapy during controlled donation after circulatory death shorten the life of potential donors?
Author(s) -
Ledoux Didier,
Delbouille MarieHélène,
Deroover Arnaud,
Lambermont Bernard,
Meurisse Michel,
Damas Pierre,
Joris Jean,
Detry Olivier
Publication year - 2014
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/ctr.12276
Subject(s) - medicine , donation , organ donation , surgery , transplantation , economics , economic growth
Controlled donation after circulatory death ( DCD ) remains ethically controversial. The authors developed a controlled DCD protocol in which comfort therapy is regularly used. The aim of this study was to determine whether this policy shortens the DCD donors' life. Methods The authors retrospectively analyzed prospectively collected data on patients proposed for DCD at the University Hospital of Liege, Belgium, over a 56‐month period. The survival duration of these patients, defined as duration between the time of proposal for DCD and the time of circulatory arrest, was compared between patients who actually donated organs and those who did not. Results About 128 patients were considered for controlled DCD and 54 (43%) became donors. Among the 74 non‐donor patients, 34 (46%) objected to organ donation, 38 patients (51%) were denied by the transplant team for various medical reasons, and two potential DCD donors did not undergo procurement due to logistical and organizational reasons. The survival durations were similar in the DCD donor and non‐donor groups. No non‐donor patient survived. Conclusions Survival of DCD donors is not shortened when compared with non‐donor patients. These data support the ethical and respectful approach to potential DCD donors in the authors' center, including regular comfort therapy.

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