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Cold ischemic time is critical in outcomes of expanded criteria donor renal transplantation
Author(s) -
Kim Suh Min,
Ahn Sanghyun,
Min Sang Il,
Park Daedo,
Park Taejin,
Min Seung Kee,
Kim Sang Joon,
Ha Jongwon
Publication year - 2012
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/ctr.12034
Subject(s) - medicine , urology , transplantation , single center , surgery , kidney , kidney transplantation , machine perfusion , liver transplantation
The outcomes of expanded criteria donor ( ECD ) kidneys have been reported to be inferior compared with standard criteria donor ( SCD ) kidneys. However, the graft survival rate of ECD is not so inferior to SCD in K orea. The purposes of this study were to compare the outcomes of ECD kidneys with SCD kidneys and identify the influencing factors. We retrospectively studied 143 deceased donor transplants from A ugust 2006 to J une 2010. The patients were divided into SCD (n = 117) and ECD (n = 26) by UNOS criteria. The one‐ and three‐yr graft survival rates of SCD and ECD (99.1% and 94.4% vs. 100% and 92.9%, respectively, p = 0.15) were not significantly different between groups. The mean cold ischemic time ( CIT ) was 3.8 ± 2.2 h. When compared the outcome of ECD kidneys with data reported by O rgan P rocurement and T ransplantation N etwork and the S cientific R egistry of T ransplant R ecipients ( OPTN / SRTR ) (one‐ and three‐yr graft survival rate: 86.7% and 73.2%), the graft survival rate of our center was superior. In OPTN / SRTR data, transplant with CIT shorter than 11 h was only 20%. The outcomes of ECD grafts are outstanding and comparable with SCD grafts in our center, and the only distinguishing factor is markedly short CIT . Finishing the allocation before organ recovery and immediate operations after recovery could shorten the CIT .