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Noninvasive ventilation and renal replacement therapy in do‐not‐intubate order critically ill patients: A brief report
Author(s) -
Catalanotti Vito,
Pisani Lara,
Betti Sara,
Bensai Serena,
Prediletto Irene,
Fasano Luca,
Nava Stefano
Publication year - 2019
Publication title -
the clinical respiratory journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.789
H-Index - 33
eISSN - 1752-699X
pISSN - 1752-6981
DOI - 10.1111/crj.13023
Subject(s) - medicine , critically ill , intensive care medicine , renal replacement therapy , noninvasive ventilation , ventilation (architecture) , rescue therapy , mechanical ventilation , surgery , anesthesia , engineering , mechanical engineering
Multiple organ failure has been considered a contraindication for noninvasive ventilation (NIV). Materials and methods We described the outcome of Do‐not‐Intubate (DNI) patients with acute respiratory failure, treated with NIV and, subsequently, necessitating renal replacement therapy (RRT). Results and discussion Seven patients admitted to our Respiratory Intensive Care Unit, developed Acute Kidney Injury (AKI) during NIV treatment and received RRT for 12.8 ± 8 days together with NIV. All the patients but one, discontinued renal support because they regained a satisfactory urinary output; nevertheless mortality rate was high (71%). Conclusion Our data suggest that RRT could be feasible together with NIV. RRT was associated with an acute improvement in renal function but did not modify the mortality rate.

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