Open AccessOutcome of pleurodesis using different agents in management prolonged air leakage following lung resection
Author(s) -
Jabłoński Sławomir,
Kordiak Jacek,
Wcisło Szymon,
Terlecki Artur,
Misiak Piotr,
SantorekStrumiłło Edyta,
Lazarek Jerry,
Kozakiewicz Marcin
Publication year - 2018
Publication title -
the clinical respiratory journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.789
H-Index - 33
eISSN - 1752-699X
pISSN - 1752-6981
DOI - 10.1111/crj.12509
Subject(s) - medicine , pleurodesis , leakage (economics) , lung , resection , intensive care medicine , anesthesia , surgery , pneumothorax , economics , macroeconomics
Abstract Background and Aims Prolonged air leaks (PAL) are a common problem after pulmonary resection. PAL can be a source of significant complications. One of the treatment options is chemical pleurodesis. Material and Methods The efficiency of three methods of treatment of PAL after lung resection was evaluated. In Iodine_ group aqueous iodine solution (lat.Tinctura Jodi) was applied intrapleurally (30 patients); in Doxycycline_group (34 patients) 200 mg of Doxycyclin was given and in Drainage_group 35 patients were applied Lidocaine solution only. Results The group investigated was similar with regard to age [ F = 0.04, P = 0.96] and the amount of air leakage (approx. 462 mL/min). The shortest drainage time and hospital stay was observed in the Iodine_group [10.57, P < 0.001]. However, this therapy was connected with strongly perceptible chest pain ( P < 0.0001]). The number of case of pneumothorax recurrence was low and it was the same was seen in other methods of treatment [ F = 0.87, P = 0.42]. Allergic reactions were not observed. The number of episodes of tachycardia, hypotension, dyspnea, pneumonia, subcutaneus empyema, fluid collection, emphysema, pneumothorax recurrence and number of re‐thoracotomies were statistically similar in all three methods of treatment. Conclusion Iodine pleurodesis can be considered as one of possible treatment methods of PAL after lung resection as it showed favorable results compared with Doxycycline pleurodesis or drainage alone regarding duration of air leakage, hospitalization and pneumothorax recurrence with only slightly increased pleural pain.