Open AccessPrimary localized tracheobronchial amyloidosis presenting with massive hemoptysis: a case report and literature review
Author(s) -
Zhang Liqin,
Zhao Yichao,
Wang Xiaowei,
Yang Jian,
Lu Zhiwei,
Cheng Yusheng
Publication year - 2017
Publication title -
the clinical respiratory journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.789
H-Index - 33
eISSN - 1752-699X
pISSN - 1752-6981
DOI - 10.1111/crj.12301
Subject(s) - medicine , bronchoscopy , respiratory tract , amyloidosis , auscultation , radiology , lung , biopsy , pathology , respiratory system
Primary localized tracheobronchial amyloidosis ( TBA ) is a rare respiratory tract dysfunction, which is a heterogeneous group of diseases involving abnormal extracellular deposition of amyloid and autologous fibrillar protein material in β‐pleated sheets. A 64‐year‐old man was referred to our hospital because of hemoptysis. Physical examination showed decreased breath sounds in the right lung on auscultation. Chest computed tomography scan displayed multiple nodules with varied size in main bronchia around bilateral hilus of the lung. After admission, bronchoscopy was performed for this patient, and roughness of mucosa in trachea and multiple nodules in respiratory tract were observed. Through further tissue biopsy, the diagnosis of primary TBA was confirmed.