Open AccessImprovement of the trigger of a ventilator for non‐invasive ventilation in children: bench and clinical study
Author(s) -
Khirani Sonia,
Louis Bruno,
Leroux Karl,
Ramirez Adriana,
Lofaso Frédéric,
Fauroux Brigitte
Publication year - 2016
Publication title -
the clinical respiratory journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.789
H-Index - 33
eISSN - 1752-699X
pISSN - 1752-6981
DOI - 10.1111/crj.12254
Subject(s) - medicine , ventilation (architecture) , noninvasive ventilation , anesthesia , bench to bedside , intensive care medicine , mechanical ventilation , engineering , medical physics , mechanical engineering
Background and Aims Even though numerous ventilators are licensed for a use in children, very few have been specifically developed for this age range. Therefore, home ventilators may not be able to adequately synchronize with the child's respiratory effort, and the inspiratory triggers ( IT s) of assist modes are not always appropriate for children. The aim of the study was to test the improvement of the IT of a ventilator on a pediatric bench and in pediatric patients. Methods A classical IT (ITc) and an improved IT [non‐invasive ventilation ( NIV ) + IT ] were tested on a bench with six pediatric profiles and in six young patients (mean age 14.1 ± 2.7 years old) requiring long‐term NIV . Results On the bench, trigger time delays (Δ T ) and trigger pressures (Δ P ) were reduced with the NIV + IT as compared with the ITc (Δ T : 0.481 ± 0.332 vs 0.079 ± 0.022 s for ITc and NIV + IT , respectively, P = 0.027; Δ P : −1.40 ± 0.70 vs −0.42 ± 0.28 cm H 2 O for ITc and NIV + IT , respectively, P = 0.046). The clinical study confirmed the decrease in Δ T (0.267 ± 0.061 vs 0.178 ± 0.074 s for ITc and NIV + IT , respectively, P = 0.024) and Δ P (−0.68 ± 0.26 vs −0.39 ± 0.11 cm H 2 O for ITc and NIV + IT , respectively, P = 0.030). Conclusions The sensitivity of the IT of a ventilator can be improved for pediatric use. The improvements observed on the bench study were confirmed in pediatric patients.