Open AccessEndogenous lipoid pneumonia preceding diagnosis of pulmonary alveolar proteinosis
Author(s) -
Antoon James W.,
Hernandez Michelle L.,
Roehrs Phillip A.,
Noah Terry L.,
Leigh Margaret W.,
Byerley Julie S.
Publication year - 2016
Publication title -
the clinical respiratory journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.789
H-Index - 33
eISSN - 1752-699X
pISSN - 1752-6981
DOI - 10.1111/crj.12197
Subject(s) - pulmonary alveolar proteinosis , medicine , etiology , pneumonia , pathology , autopsy , immunology , differential diagnosis , lung , dermatology
Pulmonary alveolar proteinosis ( PAP ) is an under‐reported and under‐diagnosed condition, with a high percentage of cases found on autopsy or late stage disease. The etiology of PAP includes genetic, primary (anti‐granulocyte‐macrophage colony‐stimulating factor antibodies) and secondary (oncologic, rheumatologic, infectious, chemical and immunologic) causes. Here, we present the first reported pediatric case of endogenous lipoid pneumonia and non‐specific interstitial pneumonitis preceding the development of PAP .