Open AccessAssessment of the relationship between right ventricular function and the severity of obstructive sleep‐disordered breathing
Author(s) -
Tanaka Yosuke,
Hino Mitsunori,
Mizuno Kyoichi,
Gemma Akihiko
Publication year - 2014
Publication title -
the clinical respiratory journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.789
H-Index - 33
eISSN - 1752-699X
pISSN - 1752-6981
DOI - 10.1111/crj.12051
Subject(s) - medicine , sleep disordered breathing , cardiology , ventricular function , breathing , sleep (system call) , obstructive sleep apnea , anesthesia , computer science , operating system
Some complications of obstructive sleep‐disordered breathing ( OSDB ), such as heart failure including right ventricular ( RV ) overload, are more serious than an increase of the apnea–hypopnea index ( AHI ) or respiratory disturbance index ( RDI ). These serious complications may contribute to the worsening of OSDB . Objective To explore the relationship between RV function in OSDB patients while awake and the severity of OSDB . Methods Fifty‐eight patients were evaluated to determine the cause of OSDB and were subjected to various examinations, including cardiac ultrasonography. Of them, 54 were included in this analysis. Results Isovolumetric relaxation time decreased as AHI increased to about 40 events/h and increased when AHI increased beyond 40 events/h. The total ejection isovolume index increased as AHI increased to approximately 35 events/h and decreased when AHI increased beyond 35 events/h. Conclusions RV function gradually deteriorated from the early stages of obstructive sleep apnea syndrome, even though there was no apparent increase in pulmonary artery pressure. The results of this study indicated that the progression of OSDB correlated with RV function determined in patients while awake. Further studies are required to clarify this relationship, including assessment of components of RV function.