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Reproducibility of pulse wave velocity and augmentation index derived from non‐invasive occlusive oscillometric tonometry analysis in adolescents
Author(s) -
Haapala Eero A.,
Veijalainen Aapo,
Kujala Urho M.,
Finni Taija
Publication year - 2019
Publication title -
clinical physiology and functional imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 67
eISSN - 1475-097X
pISSN - 1475-0961
DOI - 10.1111/cpf.12528
Subject(s) - repeatability , medicine , reproducibility , coefficient of variation , pulse wave velocity , intraclass correlation , bioelectrical impedance analysis , limits of agreement , cardiology , body mass index , nuclear medicine , blood pressure , mathematics , statistics
Summary The aim of this study was to investigate the short‐term reproducibility of aortic pulse wave velocity ( PWV ao) and augmentation index ( AI x%) assessed by the non‐invasive oscillometric device. Altogether of 55 (19 boys, 36 girls) adolescents 16–19‐years‐of‐age participated in the study. PWV ao and AI x% were measured during the same laboratory visit at 2 min intervals using the Arteriograph™ device. Peak oxygen uptake (V̇O 2peak ) was assessed by the maximal exercise test on a cycle ergometer and body fat percentage by bioelectrical impedance analysis. We studied reproducibility using intraclass correlation coefficients ( ICC ), coefficient variation with the root‐means‐square method expressed as percentages ( CV %), and 95% limit of agreement (95% LA ) and coefficient repeatability of the Bland‐Altman plot. ICC for PWV ao was 0·90, CV % 3·7 and the limits of agreement were −0·70 and 0·58 with a coefficient repeatability of 0·65. ICC for AI x% was 0·88, CV % 29·1%, and the limits of agreement were −6·8 and 7·1 with a coefficient repeatability of 6·9. No relevant differences in ICC , CV %, and coefficient repeatability for PWV ao between adolescents with higher or lower V̇O 2peak or body fat percentage were observed. For AI x%, ICC was lower, CV % higher and coefficient repeatability higher in adolescents with higher V̇O 2peak or lower body fat percentage than in adolescents with lower V̇O 2peak or higher body fat percentage. Short‐term reproducibility of Arteriograph™‐derived PWV ao was relatively good and was not affected by V̇O 2peak or adiposity. However, the reproducibility of AI x% was modest especially among adolescents with higher V̇O 2peak and lower body fat percentage.