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A new equation to predict peak VO 2 in obese patients during cardiopulmonary exercise testing
Author(s) -
Barbosa Alan Carlos Brisola,
Sperandio Evandro Fornias,
Gonze Bárbara de Barros,
Spina Giovanna Domingues,
Arantes Rodolfo Leite,
Gagliardi Antônio Ricardo de Toledo,
Romiti Marcello,
Dourado Victor Zuniga
Publication year - 2018
Publication title -
clinical physiology and functional imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 67
eISSN - 1475-097X
pISSN - 1475-0961
DOI - 10.1111/cpf.12438
Subject(s) - medicine , limits of agreement , cardiology , physical therapy , nuclear medicine
Summary We aimed to develop an equation to predict peak VO 2 in obese subjects undergoing CPET . In addition, we evaluated and compared three published equations. We randomized 346 obese subjects undergoing CPET into a group for developing the equation ( n = 272) and a group for cross‐validation ( n = 74), compared through the Bland and Altman method. Height, sex and age were responsible for 85·5% of total variability of the peak VO 2. Additional 1% and 0·7% of the variability were, respectively, explained by physical inactivity and diabetes. The equation devised was as follows:peakVO 2mlmin − 1= − 677· 8+ ( 2135 · 9× height m ) + ( 706 · 8×sex males = 1 ; females = 0 )− ( 15 · 5× age years ) − ( 161·1 × physicalinactivity yes = 1 ; no = 0 )− ( 176 · 3 × diabetes yes = 1 ; no = 0 ) .The mean difference between the estimated and measured peak VO 2 was 7 ml min −1 , with a 23·9% bias. Published equations overestimated the peak VO 2 by 35·3%, 49·1% and 46·2% bias. The equation developed in this study performed better in predicting peak VO 2 in obese adults improving ramp protocol design and CRF evaluations in obese subjects.