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Imaging and identification of brown adipose tissue on CT scan
Author(s) -
Prodhomme Hugo,
Ognard Julien,
Robin Philippe,
Alavi Zarrin,
Salaun PierreYves,
Ben Salem Douraied
Publication year - 2018
Publication title -
clinical physiology and functional imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 67
eISSN - 1475-097X
pISSN - 1475-0961
DOI - 10.1111/cpf.12373
Subject(s) - brown adipose tissue , medicine , adipose tissue , white adipose tissue , context (archaeology) , positron emission tomography , nuclear medicine , computed tomography , radiology , biology , paleontology
Summary Two types of adipose tissue ( AT ) have been described in the field of physiology: white (W) and brown (B) AT . Although WAT is well identified on human imaging, BAT imaging aspect remains to be further explored. The aim of this study was to investigate imaging aspect of BAT and its identification on CT (computed tomography) with iodine‐based contrast media injection. We retrospectively reviewed 464 positron emission tomography ( PET )/ CT , performed during 21 months on adults younger than 37 years. In 39 cases only, the PET revealed the presence of activated BAT . ROI was placed on both white and brown adipose tissue simultaneously on both PET and CT . Several patients’ characteristics (blood sugar level, gender, age, body mass index) as well as BAT and WAT parameters were assessed. Mean CT densities for WAT and BAT were −99·5 HU versus −32·6, mean SUV were 1·38 versus 13·2 and SUV max were 1·79 versus 16·57, respectively. We found a statistically significant inverse relation between BMI and BAT density. BAT has a higher density than WAT . In this manner, BAT can be misinterpreted as an infiltration of adipose tissue in neoplasic and inflammatory context. Contrast‐enhanced CT scan allows visualization and identification of BAT .