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A study of the association with blood pressure difference causing body temperature ≥37·5°C and hypertension in department of primary care
Author(s) -
Shinji Maeda
Publication year - 2013
Publication title -
clinical physiology and functional imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 67
eISSN - 1475-097X
pISSN - 1475-0961
DOI - 10.1111/cpf.12050
Subject(s) - medicine , blood pressure , cardiology , odds ratio , diabetes mellitus , heart rate , endocrinology
Summary Previous studies reported the relationship between significant blood pressure difference (Δ BP ) and early atherosclerotic markers. Although it is known that body temperature is associated with BP and blood flow, as measured on Korotkoff sound graph ( KSG ), as well as heart rate and sympathetic nerve activity, it remains unclear whether moderate fever (≥37·5°C) can be caused by significant Δ BP . Δ BP was calculated by subtracting the BP of the left arm from that of the right arm. The aim of our study was to investigate whether an association exists among Δ BP , body temperature, hypertension and KSG area ratio in 1802 new outpatients examined in a seated position in routine clinical practice. Our study documented that absolute systolic blood pressure difference (|Δ SBP |) ≥ 10 mmHg (observed in 14·6% of the patients) was associated with a significantly higher heart rate, moderate fever, tachycardia and hypertension. In multivariate analysis, the odds ratios ( OR s) of |Δ SBP | ≥ 10 mmHg showed significant associated markers of body temperature and hypertension, while the OR s of KSG area ratio ≥ 170% showed significant associated markers of sex, age, body temperature, hypertension, diabetes mellitus, prior vascular event and smoking. In conclusion, our study of new outpatients in the department of primary care demonstrated that |Δ SBP | ≥ 10 mmHg and KSG area ratio ≥ 170% were associated with moderate fever and hypertension. Furthermore, our study suggests that the association of moderate fever with |Δ SBP | ≥ 10 mmHg and KSG area ratio ≥ 170% is physiologic as well as pathologic.