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Dutch validation of the low anterior resection syndrome score
Author(s) -
Hupkens B. J. P.,
Breukink S. O.,
Olde Reuver of Briel C.,
Tanis P. J.,
de Noo M. E.,
van Duijvendijk P.,
van Westreenen H. L.,
Dekker J. W. T.,
Chen T. Y. T.,
Juul T.
Publication year - 2018
Publication title -
colorectal disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.029
H-Index - 89
eISSN - 1463-1318
pISSN - 1462-8910
DOI - 10.1111/codi.14228
Subject(s) - medicine , intraclass correlation , quality of life (healthcare) , interclass correlation , total mesorectal excision , colorectal cancer , physical therapy , population , convergent validity , test (biology) , cancer , surgery , psychometrics , patient satisfaction , clinical psychology , paleontology , nursing , environmental health , biology , internal consistency
Abstract Aim The aim of this study was to validate the Dutch translation of the low anterior resection syndrome ( LARS ) score in a population of Dutch rectal cancer patients. Method Patients who underwent surgery for rectal cancer received the LARS score questionnaire, a single quality of life (QoL) category question and the European Organization for Research and Treatment of Cancer ( EORTC ) QLQ ‐C30 questionnaire. A subgroup of patients received the LARS score twice to assess the test–retest reliability. Results A total of 165 patients were included in the analysis, identified in six Dutch centres. The response rate was 62.0%. The percentage of patients who reported ‘major LARS ’ was 59.4%. There was a high proportion of patients with a perfect or moderate fit between the QoL category question and the LARS score, showing a good convergent validity. The LARS score was able to discriminate between patients with or without neoadjuvant radiotherapy ( P = 0.003), between total and partial mesorectal excision ( P = 0.008) and between age groups ( P = 0.039). There was a statistically significant association between a higher LARS score and an impaired function on the global QoL subscale and the physical, role, emotional and social functioning subscales of the EORTC QLQ ‐C30 questionnaire. The test–retest reliability of the LARS score was good, with an interclass correlation coefficient of 0.79. Conclusion The good psychometric properties of the Dutch version of the LARS score are comparable overall to the earlier validations in other countries. Therefore, the Dutch translation can be considered to be a valid tool for assessing LARS in Dutch rectal cancer patients.