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Evidence for radiological and histopathological prognostic importance of detecting extramural venous invasion in rectal cancer: recommendations for radiology and histopathology reporting
Author(s) -
Chand M.,
Palmer T.,
Blomqvist L.,
Nagtegaal I.,
West N.,
Brown G.
Publication year - 2015
Publication title -
colorectal disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.029
H-Index - 89
eISSN - 1463-1318
pISSN - 1462-8910
DOI - 10.1111/codi.12920
Subject(s) - medicine , histopathology , radiological weapon , radiology , cancer , colorectal cancer , histopathological examination , general surgery , pathology
Extramural venous invasion (EMVI) is widely regarded as an adverse prognostic feature in rectal cancer. Whilst the effect of venous invasion has been studied for more than seven decades, Talbot’s study from St Mark’s Hospital in 1980 was the first to specify the importance of extramural vs intramural venous invasion and show that it was only invasion of tumour into the extramural veins that had a prognostic effect [1]. However, the current literature is somewhat confusing, which is most probably due to heterogeneity of definitions. We discuss some of the available evidence and offer guidance on the optimal criteria for both histopathological and radiological detection of EMVI within the context of modern management of rectal cancer.