Premium
Prevalence and trend of allergen sensitization in patients referred for patch testing with a final diagnosis of psoriasis: N orth A merican C ontact D ermatitis G roup data, 2001‐2016
Author(s) -
Silverberg Jonathan I.,
Hou Alexander,
DeKoven Joel G.,
Warshaw Erin M.,
Maibach Howard I.,
Atwater Amber R.,
Belsito Donald V.,
Zug Kathryn A.,
Taylor James S.,
Sasseville Denis,
Fransway Anthony F.,
DeLeo Vincent A.,
Pratt Melanie D.,
Reeder Margo J.,
Fowler Joseph F.,
Zirwas Matthew J.,
Marks James G.,
Dunnick Cory A.,
Houle MarieClaude
Publication year - 2021
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.13877
Subject(s) - psoriasis , medicine , dermatology , patch test , allergen , allergic contact dermatitis , atopic dermatitis , generalized pustular psoriasis , contact dermatitis , sensitization , patch testing , allergy , immunology
Abstract Background Little is known about the relationship between psoriasis and allergic contact dermatitis (ACD). Objective To examine the associations with ACD, related clinical characteristics, and common positive and clinically relevant allergens of patients with a final diagnosis of psoriasis who were referred for patch testing. Methods Retrospective analysis of 38 723 patients from the North American Contact Dermatitis Group. Results Patients with a final diagnosis of psoriasis had lower proportions of ACD than those without psoriasis (32.7% vs 57.8%). In multivariable logistic regression models, psoriasis was inversely associated with female sex, Black or Asian race, and history of atopic dermatitis and hay fever. Patients with a final diagnosis of psoriasis were less likely to have one or more positive allergic patch‐test reactions or to have a current clinically relevant patch‐test reaction to the majority of the most commonly positive and/or relevant allergens. The most clinically relevant allergens included nickel sulfate, methylisothiazolinone, and fragrance mix I. Conclusion Approximately one‐third of patients who were referred for patch testing with a final diagnosis of psoriasis were also diagnosed with ACD. In select patients with suspected psoriasis who also have a clinical presentation suggestive of ACD, patch testing may be helpful.