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Hyperkeratotic hand eczema compared to other subgroups of hand eczema – a retrospective study with a follow‐up questionnaire
Author(s) -
van der Heiden Janique,
Agner Tove,
Rustemeyer Thomas,
Clemmensen Kim K. B.
Publication year - 2018
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.12945
Subject(s) - hand eczema , medicine , retrospective cohort study , dermatology , outpatient clinic , population , pediatrics , surgery , allergy , contact dermatitis , immunology , environmental health
Summary Background Only a few clinical trials on hand eczema have included further classification into subtypes, and there is a need for studies evaluating the present classifications. Objectives To examine differences in demographic factors, lifestyle factors and severity between subgroups of hand eczema patients, with a focus on hyperkeratotic hand eczema. Methods This was a retrospective study including hand eczema patients referred to the outpatient dermatological clinic, Bispebjerg Hospital, between January 2013 and July 2014. The study comprises information on subdiagnoses, treatment and foot eczema from patient files, as well as a follow‐up questionnaire. Results A total of 120 patients were included, 10 of whom were diagnosed with hyperkeratotic hand eczema. A significantly higher proportion of the patients with hyperkeratotic hand eczema were male ( p = 0.002) and received systemic or ultraviolet (UV) treatment ( p = 0.026). The frequency of tobacco smoking was significantly higher in patients with hyperkeratotic hand eczema ( p = 0.016), as well as in the other subgroups combined ( p = 0.049), than in the background population. Conclusions Studies evaluating the subdiagnoses of hand eczema are needed, to further validate the classification system, and to provide more detailed information about demographic factors, severity and possible risk factors for different subgroups of hand eczema.