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Hand eczema and wet work: dose–response relationship and effect of leaving the profession
Author(s) -
Carøe Tanja K.,
Ebbehøj Niels E.,
Bonde Jens P. E.,
Flachs Esben M.,
Agner Tove
Publication year - 2018
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.12934
Subject(s) - hand eczema , medicine , occupational medicine , work (physics) , occupational exposure , occupational safety and health , work intensity , dermatology , physical therapy , environmental health , allergy , contact dermatitis , immunology , pathology , mechanical engineering , engineering
Summary Background Wet work is an important risk factor for occupational hand eczema. Objectives To examine the effect of job change in workers with occupational hand eczema caused by wet work, and to evaluate the dose–response relationship between intensity of wet work and eczema. Method The study is based on a subgroup (n = 954) from a descriptive, registry‐based study including all participants with occupational hand eczema caused by wet work recognized by the Danish Labour Market Insurance Authority in 2010 and 2011. A follow‐up questionnaire was sent out 4–5 years later (response 58%). Results Change of profession and being outside the labour market had a positive effect on healing and improvement of hand eczema. Inverse dose–response relationships were found between the amount of time spent with wet hands at work and healing ( p  = 0.001) and improvement ( p  < 0.001), and between the frequency of hand washing at work and healing ( p  = 0.013) and improvement ( p  < 0.001). Conclusions Leaving the profession has a positive effect on eczema; however, even minor changes in exposure to wet work were associated with healing and improvement. This information has implications with respect to advice given to patients with occupational hand eczema caused by wet work.

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