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Airborne allergic contact dermatitis caused by isothiazolinones in water‐based paints: a retrospective study of 44 cases
Author(s) -
Amsler Emmanuelle,
Aerts Olivier,
RaisonPeyron Nadia,
Debons Michèle,
Milpied Brigitte,
GiordanoLabadie Françoise,
Waton Julie,
FerrierLe Bouëdec Marie C.,
Lartigau Isabelle,
Pecquet Catherine,
Assier Haudrey,
AvenelAudran Martine,
Bernier Claire,
Castelain Florence,
Collet Evelyne,
Crépy MarieNoëlle,
Genillier Nathalie,
Girardin Pascal,
Pralong Pauline,
Tetart Florence,
VitalDurand Dominique,
Soria Angele,
Barbaud Annick
Publication year - 2017
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.12795
Subject(s) - medicine , allergic contact dermatitis , dermatology , contact dermatitis , allergy , epidemiology , patch test , immunology
Summary Background Airborne allergic contact dermatitis caused by paints containing isothiazolinones has been recognized as a health hazard. Objectives To collect epidemiological, clinical and patch test data on airborne allergic contact dermatitis caused by isothiazolinone‐containing paints in F rance and B elgium. Methods A descriptive, retrospective study was initiated by the D ermatology and A llergy G roup of the F rench S ociety of D ermatology, including methylchloroisothiazolinone ( MCI )/methylisothiazolinone ( MI )‐ and/or MI ‐sensitized patients who developed airborne allergic contact dermatitis following exposure to isothiazolinone‐containing paint. Results Forty‐four cases were identified, with mostly non‐occupational exposure (79.5%). Of the patients, 22.5% of also had mucosal symptoms. In several cases, the dermatitis required systemic corticosteroids (27.3%), hospitalization (9.1%), and/or sick leave (20.5%). A median delay of 5.5 weeks was necessary to enable patients to enter a freshly painted room without a flare‐up of their dermatitis. Approximately one‐fifth of the patients knew that they were allergic to MI and/or MCI/ MI before the exposure to paints occurred. Conclusion Our series confirms that airborne allergic contact dermatitis caused by paints containing isothiazolinones is not rare, and may be severe and long‐lasting. Better regulation of isothiazolinone concentrations in paints, and their adequate labelling, is urgently needed.