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Allergic contact dermatitis caused by panthenol: a rare but relevant sensitizer
Author(s) -
Clerens Ilse,
Goossens An
Publication year - 2017
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.12685
Subject(s) - allergic contact dermatitis , dermatology , contact dermatitis , medicine , chemistry , intensive care medicine , allergy , immunology
Panthenol is the alcohol analogue of panthothenic acid, known as vitamin B5, which is required for the biosynthesis of coenzyme A in cells. This compound exists as two stereoisomers, D-pathenol and L-panthenol, only the former being biologically active (1). It is a common ingredient in pharmaceutical products, for example in topical treatments for rhinitis, conjunctivitis, sunburn, and wounds, mainly because of its anti-inflammatory and wound-healing properties. Moreover, it is used in cosmetics, such as hair lotions, sunscreens, nail polish, and make-up, for its moisturizing and conditioning properties (1–4).