Premium
The reactivity of the back revisited. A re there differences in reactivity in different parts of the back?
Author(s) -
Björk AnnKristin,
Bruze Magnus,
Engfeldt Malin,
Nielsen Christel,
Svedman Cecilia
Publication year - 2017
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.12657
Subject(s) - patch test , reproducibility , patch testing , contact allergy , reactivity (psychology) , allergic contact dermatitis , allergy , contact dermatitis , medicine , nickel allergy , serial dilution , dermatology , immunology , mathematics , statistics , pathology , alternative medicine
Summary Background In the contact dermatitis literature, it is regularly stated that the patch test reactivity on various areas of the back differs, which might have a large impact on the reproducibility of patch testing. Objectives To investigate the reproducibility of patch testing on the upper back with regard to the left as opposed to the right side, and the medial as opposed to the lateral part of the upper back. The reproducibility over time and with regard to the reactivity pattern was also investigated. Methods Thirty‐one subjects with contact allergy to the metals gold (n = 19) or nickel (n = 12) were patch tested with serial dilutions, in triplicate applications, on different locations on the upper back. The F riedman test was used for statistical calculations. Results No significant differences in the reactivity of the back were found. In all gold‐allergic patients and 11 of 12 nickel‐allergic patients, the allergy could be reproduced with regard to previous patch testing, but the degree of reactivity differed. Conclusions When a high level of standardization of the patch test technique with the same test system was used, there were no differences in patch test reactions and sites of application on the upper back.