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ESSCA results with the baseline series, 2002–2012: p ‐phenylenediamine
Author(s) -
Schuttelaar MarieLouise A.,
Vogel Tatiana A.,
Rui Francesca,
Kręcisz Beata,
ChomiczewskaSkora Dorota,
KiećŚwierczyńska Marta,
Uter Wolfgang,
Larese Filon Francesca
Publication year - 2016
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.12583
Subject(s) - medicine , sensitization , allergy , p phenylenediamine , dermatology , grading (engineering) , hair dyes , contact allergy , atopic dermatitis , contact dermatitis , demography , immunology , chemistry , civil engineering , materials science , organic chemistry , sociology , dyeing , engineering , composite material
Summary Background Allergic contact dermatitis caused by p ‐phenylenediamine ( PPD ) is common among all age groups and both sexes. Monitoring of prevalence and intensity of sensitization is important. Objective To evaluate contact allergy to PPD in E urope, and to compare reaction intensities in different E uropean regions. Methods Data collected by the E uropean S urveillance S ystem on C ontact A llergies ( ESSCA ) network between 2002 and 2012 from 12 E uropean countries were analysed regarding prevalence, grading of positive reactions to PPD , and relevance. Results A total of 99 926 PPD ‐positive patients from 63 departments were included for analysis. The overall (2002–2012) prevalence of PPD sensitization in E urope is ∼4%. Stratified for country, the highest overall standardized prevalence was found in L ithuania, and the lowest in S lovenia. The prevalence of PPD sensitization did not decline over the years. In the southern E uropean countries, higher numbers of strong and extremely strong reactions were registered. The clinical relevance of PPD sensitization varied from half to three‐quarters. Conclusion The prevalence of PPD sensitization has not changed over time. Strong and extremely strong patch test reactions are seen more often in the S outh, probably because of the higher number of PPD ‐containing hair dye products.