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Sensitization to and allergic contact dermatitis caused by Mirvaso ® (brimonidine tartrate) for treatment of rosacea – 2 cases
Author(s) -
Bangsgaard Nannie,
Fischer Louise A. N.,
Zachariae Claus
Publication year - 2016
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.12547
Subject(s) - allergy , allergic contact dermatitis , dermatology , medicine , immunology
Rosacea is characterized by transient or persistent erythema, telangiectasia, papules and pustules primarily affecting the central facial region. Recently brimonidine tartrate gel 0.33% has been approved for the topical treatment of persistent facial erythema of rosacea (1). Allergic blepharitis caused by brimonidine in patients treated with brimonidine tartrate 0.33% eye drops has been documented (2–4), but allergic contact dermatitis caused by topical brimonidine had only been reported once before (5). We report 2 patients with rosacea who were sensitized and who developed allergic contact dermatitis following treatment with topical brimonidine 0.33%.