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Sorbitan sesquioleate; a rare cause of contact allergy in consecutively patch tested dermatitis patients
Author(s) -
Bennike Niels Højsager,
Johansen Jeanne Duus
Publication year - 2016
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.12536
Subject(s) - dermatology , allergic contact dermatitis , allergy , contact dermatitis , contact allergy , patch testing , medicine , patch test , irritant contact dermatitis , contact urticaria , immunology
Summary Background Sorbitan sesquioleate ( SSO ) has been added to fragrance mix I ( FM I ) as an emulsifier since the 1990s. Being a contact allergen itself, SSO has the potential to cause false‐positive reactions to FM I . Recent results obtained with selected FM I ‐positive patients have shown that 5% have concomitant positive reactions to SSO . Objectives To investigate the 5‐year prevalence of contact allergy to SSO and evaluate the importance of SSO allergy when patch test results for FM I are interpreted. Methods This was a retrospective database study of consecutively patch tested eczema patients (n = 4 6 3 7) from 2010 to 2014. All patients were tested with our baseline series including FM I and SSO 20% in pet. Results Sensitization to SSO was identified in 9 (0.2%) patients. The proportion of FM I ‐positive patients with concomitant positive reactions to SSO was 1.4%. Conclusions SSO is a rare cause of contact allergy, with a 5‐year prevalence of 0.2% in consecutively tested patients. Contact allergy to the emulsifier does not play a major role when the overall frequency of contact allergy to FM I is evaluated. However, to correctly diagnose individual patients, concomitant patch testing with FM I and SSO is encouraged.