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Contact dermatitis caused by efinaconazole solution for treatment of onychomycosis
Author(s) -
Hirohata Ayaki,
Hanafusa Takaaki,
MabuchiKiyohara Eriko,
Ikegami Ryuta
Publication year - 2015
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.12414
Subject(s) - health care , medicine , dermatology , family medicine , political science , law
Funding sources: None. Conflict of interest: The authors declare no conflict of interest associated with this manuscript. had suffered from ungual hyperkeratosis and itchy, scaly erythema of the interdigital web spaces for 5 years, for which he had consulted our department in September 2014. On that occasion, onychomycosis and interdigital erythrasma was diagnosed, and efinaconazole 10% topical solution (Kaken Pharmaceutical Company Limited, Tokyo, Japan) and ketoconazole cream (Janssen Pharmaceuticals Inc., Tokyo, Japan) were prescribed. At the current presentation, scaly erythema with microvesicles, erosions and crusts in the subungual area and web space and around the toenails were observed, which had started 1.5 months after treatment initiation (Fig. 1). Repeat direct microscopic examination of a skin sample on potassium hydroxide mounts did not show any fungal infection. Therefore, we diagnosed contact dermatitis caused by efinaconazole 10% topical solution, as the patient applied the solution not only to the nail but also to the skin around the nail and the web space.