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Contact and photocontact allergy to octocrylene: a review
Author(s) -
de Groot Anton C.,
Roberts David W.
Publication year - 2014
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/cod.12205
Subject(s) - cosmetics , contact allergy , dermatology , allergy , medicine , sunscreening agents , allergic contact dermatitis , ketoprofen , contact dermatitis , pharmacology , immunology , skin cancer , pathology , cancer
Summary Octocrylene is an ultraviolet ( UV)B and UVAII absorber that was introduced some 15 years ago, and is now widely used in sunscreen agents and skin care cosmetics. Since 2003, several studies, notably from F rance, B elgium, S pain, and I taly, have reported an increasing number of patients with photocontact allergy to octocrylene. This reaction is seen mainly in adult patients who have previously used topical products containing the non‐steroidal anti‐inflammatory drug ketoprofen. Photosensitization to ketoprofen leads, in many cases, to photocontact allergy to octocrylene; the mechanism of this reaction is unknown. Contact allergy to octocrylene also occurs, but is far less frequent, and is seen, in most cases, in children, resulting from the use of octocrylene‐containing sunscreen products. In this article, (photo)contact allergy to octocrylene is fully reviewed.