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A differential diagnosis of a head and neck bony lesion: Review of a case series with 18 patients with extraintestinal features of familial adenomatous polyposis
Author(s) -
Dickinson A.,
Koskenvuo L.,
Tuomainen K.,
Mäkitie A.,
Lepistö A.,
Renkonen S.
Publication year - 2018
Publication title -
clinical otolaryngology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.914
H-Index - 68
eISSN - 1749-4486
pISSN - 1749-4478
DOI - 10.1111/coa.13062
Subject(s) - medicine , head and neck , differential diagnosis , familial adenomatous polyposis , lesion , radiology , surgery , pathology , colorectal cancer , cancer
We would like to draw to the attention of head and neck surgeons the following disease that can present first to head and neck specialists with either a head and neck lump or following an incidental finding on radiological imaging. Familial Adenomatous Polyposis (FAP) is a hereditary disease caused by a mutation in the APC gene on chromosome 5, which is inherited in an autosomal dominant fashion with complete penetrance but variable expression(1). However in approximately 25% of cases it arises from a de novo mutation of the APC gene(1). This article is protected by copyright. All rights reserved.