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Quality of life in patients with allergic rhinitis: a clinical trial comparing the use of bilastine versus loratadine
Author(s) -
Locks R.B.,
Santos K.,
Silva J.
Publication year - 2017
Publication title -
clinical otolaryngology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.914
H-Index - 68
eISSN - 1749-4486
pISSN - 1749-4478
DOI - 10.1111/coa.12695
Subject(s) - loratadine , medicine , quality of life (healthcare) , otorhinolaryngology , clinical trial , outpatient clinic , anesthesia , surgery , nursing
Objectives The aim of this study was to determine whether there were differences in health‐related quality of life of patients with allergic rhinitis treated with bilastine 20 mg compared to those treated with loratadine 10 mg. Design This was a prospective randomised double‐blinded study. Setting Otolaryngology outpatient clinics in Criciúma, state of Santa Catarina, Brazil. Participants Seventy‐three patients, aged between 18 and 63 years, of whom 36 were treated with loratadine 10 mg and 37 with bilastine 20 mg with medication administered once a day for 10 days. Main outcome measures The outcome was quality of life as assessed by the modified Rhinoconjunctivitis Quality of Life Questionnaire (RQLQm), which was applied at baseline and after 10 days of treatment. Results The use of bilastine 20 mg or loratadine 10 mg significantly reduced RQLQm scores after 10 days of treatment ( P < 0.001); however, there was no statistically significant difference between the two treatment groups ( P > 0.05). Conclusions Health‐related quality of life in patients with allergic rhinitis improved significantly after 10 days of treatment with loratadine and bilastine, and the effectiveness of both was equivalent.