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The role of interventional sialendoscopy and intraductal steroid therapy in patients with recurrent sine causa sialadenitis: a prospective cross‐sectional study
Author(s) -
Capaccio P.,
Torretta S.,
Di Pasquale D.,
Rossi V.,
Pignataro L.
Publication year - 2017
Publication title -
clinical otolaryngology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.914
H-Index - 68
eISSN - 1749-4486
pISSN - 1749-4478
DOI - 10.1111/coa.12681
Subject(s) - medicine , sialadenitis , sine qua non , prospective cohort study , surgery , salivary gland , philosophy , linguistics
Objectives To verify the role of interventional sialendoscopy and steroidal ductal irrigation in patients with recurrent sialadenitis. Design A prospective, cross‐sectional pilot study. Setting University of Milan. Participants Fifty‐four patients with sine causa recurrent sialadenitis who underwent interventional sialendoscopy (group A, 36 patients) or interventional sialendoscopy followed by a intraductal steroidal irrigations (group B, 18 patients). Main outcomes measures The number of episodes of sialadenitis three and 6 months before and after sialendoscopy, and their severity assessed by means of a 0–10 pain visual analogue scale. Results In the population as a whole, a significant post‐treatment reduction in the number of episodes of 30.7 ± 5.5 after 3 months and 34.6 ± 10.2 after 6 months ( P < 0.001) and a significant reduction in pain visual analogue scale values of 4.7 ± 0.4 after 6 months ( P < 0.001) occurred. There was a statistically significant reduction in both parameters at the same time points in both treatment groups ( P ≥ 0.001), with no significant between‐group difference in pain visual analogue scale values, an albeit non‐significant trend in favour of group B in terms of the number of episodes 3 months after therapy that became significant after 6 months (11.0 ± 9.9 versus 20.5 ± 9.5; P = 0.05). Conclusions Interventional sialendoscopy is effective for the treatment of recurrent sialadenitis; the addition of intraductal steroidal irrigations seems to increase its value in the medium term. Further studies of larger case series with longer follow‐up are needed to establish the possibly primary role of steroid therapy in blocking inflammation.