Open AccessWhite matter repair and treatment strategy after intracerebral hemorrhage
Author(s) -
Jiang YiBin,
Wei KaiYan,
Zhang XuYang,
Feng Hua,
Hu Rong
Publication year - 2019
Publication title -
cns neuroscience and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.403
H-Index - 69
eISSN - 1755-5949
pISSN - 1755-5930
DOI - 10.1111/cns.13226
Subject(s) - internal capsule , white matter , intracerebral hemorrhage , medicine , basal ganglia , neuroscience , intensive care medicine , surgery , psychology , central nervous system , magnetic resonance imaging , radiology , subarachnoid hemorrhage
The predilection site of intracerebral hemorrhage (ICH) is in the basal ganglia, which is rich in white matter (WM) fiber bundles, such as cerebrospinal tract in the internal capsule. ICH induced damage to this area can easily lead to severe neurological dysfunction and affects the prognosis and quality of life of patients. At present, the pathophysiological mechanisms of white matter injury (WMI) after ICH have attracted researchers' attention, but studies on the repair and recovery mechanisms and therapy strategies remain rare. In this review, we mainly summarized the WM recovery and treatment strategies after ICH by updating the WMI‐related content by reviewing the latest researches and proposing the bottleneck of the current research.