Open AccessRisk factors for hemorrhage of brain arteriovenous malformation
Author(s) -
Shaligram Sonali S.,
Winkler Ethan,
Cooke Daniel,
Su Hua
Publication year - 2019
Publication title -
cns neuroscience and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.403
H-Index - 69
eISSN - 1755-5949
pISSN - 1755-5930
DOI - 10.1111/cns.13200
Subject(s) - arteriovenous malformation , medicine , radiosurgery , embolization , intracranial arteriovenous malformations , natural history , intracerebral hemorrhage , resection , radiology , surgery , cerebral angiography , angiography , subarachnoid hemorrhage , radiation therapy
Patients with brain arteriovenous malformation (bAVM) are at risk of intracranial hemorrhage (ICH). Overall, bAVM accounts for 25% of hemorrhagic strokes in adults <50 years of age. The treatment of unruptured bAVMs has become controversial, because the natural history of these patients may be less morbid than invasive therapies. Available treatments include observation, surgical resection, endovascular embolization, stereotactic radiosurgery, or combination thereof. Knowing the risk factors for bAVM hemorrhage is crucial for selecting appropriate therapeutic strategies. In this review, we discussed several biological risk factors, which may contribute to bAVM hemorrhage.