Open AccessKetamine‐An Update on Its Clinical Uses and Abuses
Author(s) -
Xu Jian,
Lei Hong
Publication year - 2014
Publication title -
cns neuroscience and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.403
H-Index - 69
eISSN - 1755-5949
pISSN - 1755-5930
DOI - 10.1111/cns.12363
Subject(s) - ketamine , medicine , intensive care medicine , substance abuse , chronic pain , dissociative , depression (economics) , drug , psychiatry , macroeconomics , economics
Summary This review highlights the recent clinical research that supports the therapeutic utility of ketamine as a multifaceted drug. After long‐term use as a dissociative anesthetic, it has re‐emerged as a useful agent for ameliorating pain, asthmaticus, and depression. In addition, it is also a substance of abuse. Chronic ketamine abuse over prolonged periods (weeks, months, and years) can produce toxicity to the gastrointestinal and urinary tract. In this review, we described the recent progress on its clinical uses and abuses.