Open AccessVomocytosis: What we know so far
Author(s) -
Seoane Paula I.,
May Robin C.
Publication year - 2020
Publication title -
cellular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.542
H-Index - 138
eISSN - 1462-5822
pISSN - 1462-5814
DOI - 10.1111/cmi.13145
Subject(s) - biology , cryptococcus neoformans , repertoire , host (biology) , mechanism (biology) , exocytosis , disease , pathogen , immunology , ecology , microbiology and biotechnology , genetics , epistemology , pathology , medicine , philosophy , physics , membrane , acoustics
Vomocytosis, or nonlytic exocytosis, has been reported for Cryptococcus neoformans since 2006. Since then, the repertoire of vomocytosing pathogens and host cells has increased and so have the molecular components linked to vomocytosis occurrence. Nonetheless, the mechanism underlying this phenomenon, whether it is triggered by the host or the pathogen, and how it affects disease progression are still unresolved. This review contains a summary of the main findings regarding vomocytosis and the outstanding questions puzzling scientists to this day.