Open AccessOverview of fission yeast septation
Author(s) -
Pérez Pilar,
Cortés Juan C. G.,
MartínGarcía Rebeca,
Ribas Juan C.
Publication year - 2016
Publication title -
cellular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.542
H-Index - 138
eISSN - 1462-5822
pISSN - 1462-5814
DOI - 10.1111/cmi.12611
Subject(s) - cytokinesis , biology , schizosaccharomyces pombe , microbiology and biotechnology , schizosaccharomyces , cell division , septin , mitosis , yeast , transmembrane protein , morphogenesis , cleavage furrow , cell , saccharomyces cerevisiae , biochemistry , receptor , gene
Summary Cytokinesis is the final process of the vegetative cycle, which divides a cell into two independent daughter cells once mitosis is completed. In fungi, as in animal cells, cytokinesis requires the formation of a cleavage furrow originated by constriction of an actomyosin ring which is connected to the plasma membrane and causes its invagination. Additionally, because fungal cells have a polysaccharide cell wall outside the plasma membrane, cytokinesis requires the formation of a septum coincident with the membrane ingression. Fission yeast Schizosaccharomyces pombe is a unicellular, rod‐shaped fungus that has become a popular model organism for the study of actomyosin ring formation and constriction during cell division. Here we review the current knowledge of the septation and separation processes in this fungus, as well as recent advances in understanding the functional interaction between the transmembrane enzymes that build the septum and the actomyosin ring proteins.