Premium
Positive effect of strontium‐oxide layer on the osseointegration of moderately rough titanium surface in non‐osteoporotic rabbits
Author(s) -
Fan Yanpin,
Chen Xiaoyi,
Chen Yun,
Yang Guoli,
Wang Huiming,
He Fuming
Publication year - 2017
Publication title -
clinical oral implants research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.407
H-Index - 161
eISSN - 1600-0501
pISSN - 0905-7161
DOI - 10.1111/clr.12897
Subject(s) - osseointegration , strontium , titanium , materials science , dentistry , rough surface , chemistry , medicine , metallurgy , composite material , implant , surgery , organic chemistry
Objectives To evaluate the effect of strontium‐oxide layer on new bone formation and osseointegration of sandblasted large‐grit double‐acid‐etched ( SLA ) implant. Material and methods Strontium‐oxide layer on the SLA surface was produced by hydrothermal treatment using a Sr‐containing solution. The surface topographies, roughness, hardness values, chemical elements and ionic release of SLA and the strontium‐containing SLA (Sr‐ SLA ) surface were measured by special instruments separately. Sixty‐four SLA and Sr‐ SLA implants were inserted into the proximal tibiae and femoral condyles of sixteen non‐osteoporotic New Zealand white rabbits. The biological effects were evaluated by removal torque ( RTQ ) testing and histomorphometric analysis after 3 and 6 weeks of implantation. Results The surface characteristics showed Sr‐ SLA surfaces with dotted nanostructures can release appropriate amount of strontium ions into surrounding tissue till 14 days. In vivo , the Sr‐ SLA implants presented significantly higher RTQ than SLA implants at 3 and 6 weeks ( P < 0.05). The Sr‐ SLA implants presented higher bone‐to‐implant contact ( BIC ) than SLA implants in cortical bone at 3 and 6 weeks ( P < 0.05). The bone area was slightly higher for the Sr‐ SLA implants at 3 and 6 weeks ( P > 0.05). Conclusions The strontium‐oxide layer on the SLA surface has the potential to improve implant osseointegration in non‐osteoporotic rabbits.