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Radiographic and histological evaluation of deproteinized bovine bone mineral vs. deproteinized bovine bone mineral with 10% collagen in ridge preservation. A randomized controlled clinical trial
Author(s) -
Nart Jose,
Barallat Lucía,
Jimenez Daniel,
Mestres Jaume,
Gómez Alberto,
Carrasco Miguel Angel,
Violant Deborah,
RuízMagaz Vanessa
Publication year - 2017
Publication title -
clinical oral implants research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.407
H-Index - 161
eISSN - 1600-0501
pISSN - 0905-7161
DOI - 10.1111/clr.12889
Subject(s) - dentistry , bone mineral , chemistry , medicine , biomedical engineering , pathology , osteoporosis
Objectives The aims of this randomized clinical trial were to compare the dimensional changes and the histological composition after using deproteinized bovine bone mineral ( DBBM ) or deproteinized bovine bone mineral with 10% collagen ( DBBM ‐C) and a collagen membrane in ridge preservation procedures. Material and methods Patients who required an extraction and a subsequent implant‐supported rehabilitation at a non‐molar site were recruited. After extraction, a cone beam computed tomography ( CBCT ) was performed and sites were randomly treated either with DBBM or DBBM ‐C plus a collagen membrane. At 5 months, before implant placement, a second CBCT was performed and a biopsy of the area was obtained. A blinded investigator superimposed the CBCT s and performed measurements to determine bone volume changes between the two time points. Additionally, a histomorphometric analysis of the biopsies was performed in a blinded manner. Results Eleven sites belonged to the DBBM group and eleven to the DBBM ‐C group. All together, a significant reduction in height and width was observed at 5 months of healing, but no statistically significant differences were observed between the DBBM and the DBBM ‐C group. The histomorphometric analysis revealed a similar composition in terms of newly formed bone, connective tissue and residual graft particles in both groups. Conclusions Deproteinized bovine bone mineral with 10% collagen showed a similar behaviour as DBBM not only in its capacity to minimize ridge contraction but also from a histological point of view. Thus, both graft materials seem to be suitable for ridge preservation procedures.